As little ghosts and goblins prepare to carry their high-capacity pillowcases through their neighborhoods to grab as much sugar as they can carry, we thought we would share some real life horror stories from our experiences providing services to vital laboratory tools. While we aren’t quite reaching the depths of twisted science like Dr. Frankenstein, there are three practices we see regularly that will chill the bones of anyone dedicated to solid, high quality liquid handling practices in the lab…
For those of us who calibrate on a daily basis, the repeated routine of pipetting may have become almost second nature. In fact, a metrology-centric calibration program should provide the standardized expertise necessary for proper performance assessment and maintenance. However, periodically brushing up on the fundamentals of practice and procedure can refresh your skills, correct errors, and remind you that even the smallest mistakes can lead to major ramifications in the lab space. Understanding your process and having mastery of your chemistry lab supplies, or biology techniques, will play a huge role in your success or failure. So let’s go back to the basics to ensure the highest quality of service and measurement at every turn with these 5 things you need to know about pipette tips:
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How much do you know about today's mechanical pipettes? Each week, in our Accuracy Matters blog, our readers can find all sorts of useful information about pipetting- best practices and tips, regulatory changes and innovative techniques. This week we're testing your knowledge!
Every year, commercial and research laboratories await the Food and Drug Administration’s (FDA) annual audit of their establishment’s compliance to the strict requirement guidelines. The FDA regulations for laboratory environments are based on the ISO 17025 standard, which focuses on the level of competency and consistency in lab methodology. For companies conducting laboratory research, the ISO 17025 standard applies to pipettes, dispensers, diluters, and burets.
In part 1 of this blog, I described the landscape of the pipette market, and the developing pipette service market, from the 1960s through the 1990s. In the 30+ years of biology, clinical and metrology lab experience I have accumulated, I recognized two significant events during the past 14 years that have significantly impacted and shaped the pipette calibration service market today. In Part 2, I will describe these events and what impacts they had.
The Early Years
The mechanical pipette (micropipette) was invented in the early 1960s and has historically become one of the most significant laboratory tools over the last 50 years. It was further developed into an adjustable micropipette in 1972. At this time, there were limited service options for pipette users, as pipette manufacturers initially guided customers toward replacement pipettes. While clinical laboratories were dominated by the MLA brand; Eppendorf, Gilson Pipetman® and Finnpipette® dominated the R&D laboratories, and new brands ensued. The pipette calibration market had yet to develop, as pipettes were mostly sent back to their manufacturers for repairs, which included lengthy turnarounds. Scientists then were at a disadvantage, as pipetting accuracy and repeatability remained largely unchecked, and laboratory procedure had to accommodate wide tolerances.
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TTE Laboratories' blog covers pipetting news that affects your science. From best pipetting practices, to pipette error prevention, regulatory compliance and innovative techniques, you can learn what the experts want you to know about Accuracy Matters.