Accuracy Matters Blog

Accuracy matters in science and TTE’s Accuracy Matters blog reports on all things related to pipetting accuracy: best pipetting practices, pipette error prevention, regulatory compliance, innovative techniques and more. If accuracy matters to you, subscribe to TTE's Accuracy Matters Blog.

The Real Cost of Laboratory Liquid Handling


The Real Cost of Laboratory Liquid Handling

Laboratories use various types of liquid handling devises every day to measure and transfer samples and reagents. Single and multichannel pipettes, repeat dispensers, bottle-top dispensers, positive displacement pipettes, etc. have been around for 40+ years and are present in almost every biopharma, medical research and clinical lab today. So, what are the costs associated with an institutions liquid handling processes? On the surface the answer appears to simply be the cost of the instruments, pipette tips and the annual or bi-annual calibration. But by digging deeper you’ll find the costs of pipetting errors, which may lead to testing failures can far outweigh all the other costs combined. Consider a typical laboratory assay in relation to the costs associated with that process; the reagents, laboratory consumables and the analyst time to estimate downstream costs of liquid handling errors. If you assume only a small percent of those errors lead to assay failures the costs associated are still high ...

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MicroPro 300


MicroPro 300

Avidien Technologies (Hudson, MA) introduced the microPro 300 pipettor at the SLAS 2017 lab automation show earlier this year and was thrilled to receive the SLAS New Product Award for their innovative new instrument.  The microPro 300 is a 96 channel pipettor that improves your assay results, frees up time for other activities and creates a healthier work environment. Because the microPro pipettes across all 96 channels simultaneously it can improve the reliability of your assay results in several ways.  First, compared with an 8 or 12 channel pipette, the well to well variability is improved because the pipette tips are all working together at the same height and angle.  Even the most experienced handheld pipette user introduces some variation by changes in tip angle and immersion depth from one transfer to the next.  Additionally, the microPro automatically controls the pipetting depth which will reduce variation from transfer to transfer, increasing overall experiment repeatability.&n ...

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TTE Laboratories Open House


TTE Laboratories Open House

TTE Laboratories open house to showcase its newly expanded Hopkinton Massachusetts facility was a great success in providing guests insight into TTE’s pipette calibration process and capabilities.  Attendee’s toured TTE’s ISO17025 accredited laboratory, learned techniques for pipetting best practices and matched pipetting skills with one of TTE’s calibration professional’s.  The newest and most efficient pipettes and laboratory products from TTE’s eCommerce website www.pipettes.com were also on display for visitors to appraise.  The day concluded with demonstrations of Brandtech’s Liquid Handling Station and the 2017 SLAS New Product Award winning Avidien 96 channel MicroPro 300, both presented live and via webcast.  Founded in 1989, TTE’s mission has always been to provide the highest quality pipette calibration services with a 24 hour turn-around time.  “However, we understood the pipette wasn’t the only issue which neede ...

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4 Benefits of Moving to Electronic Pipettes


4 Benefits of Moving to Electronic Pipettes

 Electronic pipettes can be a great choice for labs who wish to reduce their pipette failure rates, control the human impact upon the measurement, increase productivity, standardize pipetting performance across the lab, and prevent costly pipetting injuries. 



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Ask A Tech?


Ask A Tech?

Q:  My lab requires an ISO Pipette Calibration.  What do I need to do? A: Here at TTE Laboratories, we get this question frequently. Most likely, your lab requires a pipette calibration that is conducted by an ISO Accredited Laboratory. A calibration from such a lab ensures that the service provider you’ve selected holds accreditation to ISO 17025 calibration standards. These labs can offer many different service offerings, including a service especially tailored to ISO requirements. For example, we provide service to basic research labs, but they wouldn’t be required to select an “ISO Level Service”. Our ISO Service Level Certificate includes the most thorough report of each pipettes’ performance including 60 data points and summary results. Hospitals, Biotech and Pharma labs need a competent ISO Accredited provider, but may not require our ISO certificates to receive with their pipettes. When choosing service, call us. We answer the phone, and we’ll walk yo ...

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The Five Steps to Asset Control


All of us know that maintaining quality is a journey rather than a destination—change is constant, resources limited, and compliance and regulatory risks are ever present. Sometimes, however, the journey feels more like running on a treadmill than achieving real momentum. Our portal was designed to be an Enterprise Asset, Vendor, and Maintenance Management Platform, to allow your facility, lab, and quality managers transparency through the process of servicing your instruments. Through conversations the discovery was made that the most successful companies took 5 key steps to ensure their journey progresses to new heights. Read below to see what you can do to stop running in place and achieve measurable quality outcomes at your organization. Step 1: Take Stock As the saying goes, you can't manage what you can't measure. So the first step of getting all of your equipment under control is to take a full inventory of all instruments, systems, and equipment to ensure they are all accurately identified, ...

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Turn your Vendor into a Partner Coming Soon: Complete and Collaborative Asset Management


Turn your Vendor into a Partner  Coming Soon: Complete and Collaborative Asset Management

After 25 years of experience with all types and sizes of laboratories, one dominant theme has resurfaced with our customers. Laboratory pipettes are numerous, expensive, and time-consuming. They are a bother, and can take significant time to manage. They cost money to purchase and maintain.   In one way or another, customers are lacking the full control they seek over their critical laboratory equipment, and wish their vendor could do more for them under a system of accountability. At TTE, we have a proven track record of empowering our customers to make data driven decisions that secure their process, control their costs, and bring efficiency to their operations; but we’ve always hoped for the tools to improve on our ability to assist our customers.   We have some good news for you! We’ve found a way to match our desire to improve the service to our customers by meeting this challenge. The answer is our new collaborative Pipette Asset Management Platform powered by Qualer. ...

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The Value of Training


Most labs spend very little time teaching their employees how to pipette correctly. Its understandable, since using a pipette is perceived to be a basic skill that every qualified lab technician possesses. In our experience at TTE, pipette techniques and understandings vary greatly amongst a wide variety of our customers, and some lab employees don’t understand that accurate pipetting is a skill that impacts their work! Even some of the most demanding laboratories have employees that pipette incorrectly---and some have been doing so for years! In fact, 70% of all pipette error is due to the user. Lab managers know that a trained employee is certainly less likely to damage delicate equipment such as pipettes, and understand the impact of best practices upon their results. Investing in outside expert training is the best way to protect your lab results. It also reduces the amount of corrective work and deviations, which amounts to a huge cost and delay. TTE will partner with you to free you and ...

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The Dos and Don’ts of Pipette Storage and Handling


With the delicate nature of pipettes, it’s easy to damage them. This brings unnecessary costs to your lab and can cause lab managers some real frustration. Using the proper storage and handling protocols can extend the life of your equipment. Its simple, but important. Here’s a quick overview of some recognized best practices when it comes to storing, using and taking care of pipettes: Do choose the right tool for the job. Pipettes are available in a wide range of sizes and configurations — do your research and make sure scientists at your facility have access to the tools they need to get the job done right. TTE can train you on which air displacement pipette to choose for which volume, and show you other pipettes that may give you better results, such as positive displacement tools. Don’t overfill a pipette or attempt to use it for anything other than its intended purpose. Its not a stirring rod, hammer, or toy. Make sure the correct accessories are available, and th ...

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Five of the Largest Laboratory Costs Associated with Pipettes: How to Control and Reduce Them


Five of the Largest Laboratory Costs Associated with Pipettes: How to Control and Reduce Them

Unseen, Ongoing and Residual--these are words that often describe the excessive and frustrating costs associated with pipettes in the regulated laboratory. In our experience with our customers, here are five of the common sources of these costs that vary in their severity depending upon your applications. We hope we can help guide you to controlling, and perhaps eliminating some of these costs. 1.Pipette Deviations Our customers tell us that pipette deviations cause the most concern. Deviations result from a pipette failure during initial “As Found” calibration, but also occur when pipettes are found to be problematic for one reason or another during a lab process. Deviations are found to be upwards of $15,000 each due to lengthy impact investigations, lost work time, repeated experiments and other factors. A few successful countermeasures may be decreasing a calibration interval to reduce investigation time, pipette training seminars to reinforce Best Practices in order to prevent mistakes or m ...

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